ADVERSE EFFECTS FOLLOWING COVID-19 IMMUNIZATION IN KHYBER PAKHTUNKHWA: PAKISTAN

Abstract of Study:

Background:

Adverse event following immunization (AEFI) is defined as any untoward medical occurrence following immunization and does not necessarily have a causal relationship with the use of the vaccine.

Objective: To determine the adverse effects following (AEFI) of COVID 19 vaccines in the population of Khyber Pakhtunkhwa (KP).

Methods and materials:

Descriptive Cross-sectional study was conducted from June to September 2021on four hundred and three sample size of KP, selected using Cochran’s formula. AEFI’s were investigated among vaccinated male and female above 18 years. Data was collected through a self-constructed validated questionnaire and was analyzed through SPSS 25.

Results:

Out of total 403, 219 (54.3%) did not reported any AEFI, 184 (45.4%) complaint of mild and only one (0.2%) reported severe AEFI. The most common AEFI was pain at the injection site 99 (24.6%) followed by mild fever 20 (5.0%), body aches 17(4.2%) and headache 13 (3.2%). 165 (40.9 %) observed the AEFI within 48 hours while 238 (59%) observed it after 48 hours of immunization. Only 8 (2%) pregnant women and 11(2.7%) lactating mothers vaccinated themselves.

Conclusion:

Majority of the study population in KP did not suffer from any AEFIs after COVID 19 vaccination. Pregnant and lactating mothers were hesitant to vaccinate.

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