Clinical Features And Associated Comorbidities In 200 Cases Of  COVID-19 In Peshawar, Pakistan

Abstract of Study (Max 300 Words):

SARS-CoV-2 is an emerging pathogen first reported in China and rapidly spreads throughout the world. The current study focused on the prevalence of symptoms, leukocytosis, leukocytopenia, thrombocytopenia,and comorbidity in patients resulted positive for COVID-19. About 200 patients were enrolled in the study first screened by ICT and then confirmed by RT-PCR. All the patients have symptoms fever, sore throat and dry cough. However 180 (90%) patients experienced tiredness, aches  and pain all  over  the body in 193  (96%),  diarrhea in 160  (80%), conjunctivitis  in 64 (32%), headache in 177 (88%), loss of taste and smell in 49 (24%), a rash on skin, or discoloration of fingers or toes in 54 (27%), shortness of breath in 12 (8%), chest pain or pressure in 16 (8%), loss of speech and movement in 4 (2%) patients. 78 (39%) patients were found having  co-infections including 23 (29.5%) patients have liver infection, 14 (17.9%) were kidney patients,  16 (20.5%) were  heart patients and 25 (32%) were diabetic patients. Leukocytosis were found in 76 (97%) out 78 comorbid patients, while in only 2 (2.6%) non-comorbid patients had leukocytosis. Leukopenia were detected in 122 (61%) non-morbidpatients out of 200 COVID-19 patients. Thrombocytopenia were detected in 118 (59%) COVID-19 patients. The patients with previous cardiovascular diseases and other comorbid conditions may face greater risk of developing the disease into severe form. 51-60 years of individuals are at high risk  of  getting  infection.  The  hematologic  changes  are  associated  with  COVID-19  includes  thrombocytopenia, leukocytosis, and leukocytopenia.

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